Because many men experience isolated instances in their lives of not having an erection, and although these events may resolve once the cause disappears, for many, the disorder becomes an ongoing problem requiring treatment. Over the past 30 years, there have been a number of upheavals in the treatment of erectile dysfunction. In the past, the range of treatment was small and included: psychiatric treatment, the introduction of hormonal drugs, and later surgeries for genital prostheses. In the 1980s, there was a shift in the therapeutic approach as an understanding of the pathophysiology of erectile dysfunction greatly increased and there was an increased need on the part of patients to seek more successful and less invasive treatments. Over the years, a number of new treatments have been added: injections into the cervical organs, an empty pump, a blocking ring, topical ointments, surgeries to restore arterial blood flow, and surgeries to prevent venous blood leakage. Many patients understandably ask to try oral therapy first. For years, attempts at treatment with various oral medications have failed when their effects have been tested in a scientific and controlled manner. Drugs from the group of phosphodiesterase 5 inhibitors (PDE5i), in fact, marked the beginning of a revolution in the treatment of intentional erectile dysfunction, which made it possible to carry out full sexual intercourse after ingestion and thanks to which many millions of men returned to a normal sexual life. Events. Examples of such drugs are Viagra, Cialis, and Levitra.