Uroxatral (Alfuzosin) – alpha-blocker used in treatment of benign prostatic hyperplasia in men


Uroxatral (Alfuzosin) – alpha-blocker used in treatment of benign prostatic hyperplasia in men

Uroxatralis an alpha-blocker. It is used in treatment of benign prostatic hyperplasia in men with an enlarged prostate.

Synonyms: Alfuzosin is marketed in the United States by Sanofi Aventis under the brand name Uroxatral and elsewhere under the tradename Xat or Xatral, and in Egypt under name of Prostetrol.

Common use
Uroxatral is an alpha-blocker. It is used in treatment of benign prostatic hyperplasia in men with an enlarged prostate. It works by blocking receptores in the lower urinary tract, relaxing smooth muscles in the bladder neck and prostate.

Do not use this medication to treat high blood pressure.

Dosage and directions
Use Uroxatral as prescribed by your doctor. Take it orally with the same meal every day. Avoid splitting, crushing, breaking or chewing it. Swallow it the whole.

Use the medicine with caution. It can cause dizziness, drowsiness or lightheadedness. Avoid taking alcohol. Sit up or stand slowly. Avoid situations where injury could occur because of fainting. If chest pain occurs or worsens contact you doctor. If you have to have a surgery especially dental or eye surgery for cataract, tell your doctor that your are using Uroxatral.
Uroxatral can cause a prolonged and painful erection.If this in not treated it could lead to impotence and other sexual problems.
It’s not recommended to use it during pregnancy or breastfeeding.

You should not use the medicine if you have allergy to it, liver problems and you are taking alpha-blockers, macrolide antibiotics, nefazodone, azole antifungals, HIV pritease inhibitors and telithromycin.

Possible side effects
The most common side effects include:

  • drowsiness
  • dizziness
  • stomach pain
  • runny nose
  • headache
  • fatigue.

Severe side effects include:

  • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips or tongue; unusual hoarseness)
  • back pain
  • chest pain
  • dark urine
  • decreased sexual ability
  • fainting
  • fast or irregular heartbeat
  • fever, chills or persistent sore throat
  • joint pain
  • painful, prolonged erection
  • pale stools
  • severe or persistent dizziness
  • severe or persistent stomach pain
  • unusual fatigue or weakness
  • yellowing of the skin or eyes

Seek medical help if any of the listed above symptoms occurs.

Drug interaction
Tell your doctor if you take the following medicines: azole antifungals, macrolide antibiotics, amiodarone, alpha-blokers, HIV protease inhibitors, nefazodone, nitrates, phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil), or telithromycin because the risk of side effects, such as severe low blood pressure, may be increased.

Missed dose
If you miss a dose of Uroxatral, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Symptoms may include fainting , irregular heartbeat. Seek medical attention immediately if you overdosed the medicine.

Store Uroxatral at 77 F (25 C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Uroxatral out of the reach of children and away from pets.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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